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Testosterone Cream

Testosterone Cream: What You Should Know

Low energy. Low libido. Mood swings. Trouble building muscle. These aren’t just signs of getting older. They can also point to low testosterone.

Testosterone is a key hormone that supports everything from sex drive and energy to bone strength and muscle mass. While levels naturally decline with age, some men (and women!) experience a sharper drop that leads to unwanted symptoms. For these men, testosterone replacement therapy (TRT) can restore their vigor.

One of the most common treatment options is testosterone cream. Gel versions are also available. However, not all products are created equal.

Here’s what to know before you get started using testosterone cream.

Topical Testosterone Therapy

Testosterone can be delivered in several ways, including as injections. Many men prefer topical treatments due to their ease of use. These products deliver testosterone through the skin and into the bloodstream.

Testosterone Cream vs. Gel: Why the Difference Matters

In everyday conversation, the terms “cream” and “gel” are often used interchangeably.

However, in medical use, they refer to two distinct types of testosterone formulations.

The FDA has approved testosterone gels, such as:

  • AndroGel
  • Testim
  • Vogelxo

When a testosterone gel is FDA-approved, it means the product has been through a rigorous review process. It can only be approved if it’s safe, effective, and made to consistent standards.

The gel is available in pre-measured, designated doses. This ensures each application delivers a precise amount of testosterone. It’s also produced under strict guidelines to guarantee the same quality and hormone strength in every tube or packet.

Testosterone creams, on the other hand, are compounded by a pharmacy based on a doctor’s custom prescription. These are not FDA-approved. This means they haven’t gone through the same regulatory process or standardization.

This distinction matters because it affects dosing and where the product should be applied. Whether you are prescribed a gel or compounded cream, be sure to follow your doctor’s instructions closely.

Applying Testosterone Products – Location Matters

Where you apply testosterone makes a big difference in how well it’s absorbed into your bloodstream. It also plays a role in minimizing the risk of unintentionally transferring the hormone to someone else.
FDA-approved gels have specific, tested application sites:

  • AndroGel 1%: Apply to clean, dry, intact skin on the shoulders, upper arms, or abdomen unless your doctor instructs otherwise.
  • AndroGel 1.62%: Apply only to the shoulders and upper arms, not the abdomen.
  • Vogelxo: Apply to the shoulders or upper arms only. Do not apply to the abdomen.
  • Testim: Apply to the shoulders or upper arms.

Do not apply any gels to the scrotum or penis, or to skin that is cut, scraped, or irritated. Always follow your doctor’s instructions and use only on intact skin.

Compounded creams may come with different instructions. You may even be instructed to apply them to the inner thighs or scrotum. Your doctor will give specific guidance tailored to your prescription.

Always wash your hands after applying any testosterone product. You should also let the product dry before getting dressed and avoid skin contact with others until the area is fully dry.

Testosterone Therapy: What to Expect

Testosterone can help improve your energy, mood, and sex drive, sometimes within just a few weeks. But like any medication, it can cause side effects, especially if your levels go up quickly.

You might notice skin irritation where you apply it, a bit more acne, or changes in mood. Some men also experience:

  • Swelling
  • Hair changes
  • Breast tenderness
  • Higher red blood cell counts

Rarely, it can affect your prostate or heart health, which is why your doctor will keep an eye on things with regular blood tests and checkups. Remember, if anything feels off, check in with your doctor.

Don’t continue to live with the symptoms of low T. Find out if a testosterone cream or gel is right for you. Call 843.347.2450 to schedule an appointment today!

Related:

Carolina Forest Office Has Relocated!

As of February 24, 2025, our Carolina Forest office
is located at:

📍 309 Hinson Drive, Myrtle Beach, SC

How Can We Help You?

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